late 1950s first kidney transplants in London are done at St. Joseph's Hospital using living, related donors
1972 official opening of University Hospital (UH)
1973 transplant program at University Hospital begins with its first kidney transplant
1977 first liver transplant at UH
1979 University Hospital is chosen as one of five North American centres to conduct a patient study on the benefits and side effects of the new anti-rejection drug, cyclosporine
1981 first heart transplant at UH
1983 first heart-lung transplant in Canada is done at UH
1983 first pediatric heart transplant in Ontario is done at UH
1984 first pediatric liver transplant in Ontario is done at UH
1987 the Multi-Organ Transplant Unit opens, August 31
1988 our centre performs its first bowel transplant; that same year, we successfully perform a combined liver and bowel transplant, which is the first in the world
1989 our first lung transplant
1989 London's first bone marrow transplant
1990 first multi-organ transplant (liver, small bowel, stomach, and pancreas) in Canada is done at UH
1992 University Hospital, in conjunction with the University of Western Ontario, announces the start of experimental xenotransplantation
1993 our centre performs a living-related liver transplant (mother to child), the first time that this is done in Canada
1994 our liver transplant program develops a clinical pathway, reducing the average length of hospital stay, the number of medical tests, and the amount of medication without affecting patient care
1995 University Hospital and Victoria Hospital merge as the London Health Sciences Centre (LHSC)
1997 our team transplants the liver, bowel, stomach, and pancreas into a 5-month-old infant, the world's youngest recipient of a multi-organ transplant
1997 our transplant team performs its first split-liver transplant (one liver was divided into two parts so two patients could be transplanted)
2000 the first adult-to-adult living liver transplant in Canada is done at our centre
2001 London performs its 1000th liver transplant
2004 we perform our first kidney-pancreas transplant
Canadian firsts
1956 heart valves are transplanted for the first time worldwide (Toronto, Ontario)
1958 living-related kidney transplant between identical twins (Royal Victoria Hospital, Montreal, Quebec)
1963 Canada's first successful kidney transplants using deceased donors are done in Montreal (Royal Victoria Hospital), London (St. Joseph's Hospital), and Saskatoon (St. Paul's Hospital)
1968 heart transplant (Montreal, Quebec)
1970 liver transplant (Montreal, Quebec)
1974 bone marrow transplant (Toronto, Ontario)
1983 lung transplant (Toronto, Ontario), which was the first successful lung transplant in the world
1983 first heart-lung transplant in Canada is done at our centre (London, Ontario)
1986 double lung transplant (Toronto, Ontario), the world's first successful double lung transplant
1990 Canada's first multi-organ transplant (liver, small bowel, stomach and pancreas) is done (London, Ontario)
1993 living-related liver transplant (London, Ontario) is done for the first time in Canada when a parent donates a portion of her liver to her son
1995 pig liver tissue is used temporarily to keep a patient alive until a human liver became available for transplant (Montreal, Quebec)
1999 first double lung transplant using living donors (two people each donated part of a lung to the recipient) (Winnipeg, Manitoba)
2000 first adult-to-adult living liver transplant done in Canada (London, Ontario)
International milestones
1668 first bone transplant (using a piece of dog skull) into a Russian (reported in 1682 by a Dutch doctor, Meekeren)
1869 first skin grafts, reported by two surgeons in the same year (Dr. Guyon, Paris & Dr. Reverdin, Geneva)
1906 first cornea transplant reported
1908 successful knee joint transplant
1936 kidney transplants in humans are tried (Russia)
1943 dialysis machine developed
1954 first successful kidney transplant between identical twins (Peter Bent Brigham Hospital, Boston, Massachusetts)
1956 heart valves are transplanted for the first time worldwide (Toronto, Ontario)
1962 introduction of the anti-rejection drug, Imuran (azathioprine)
1962 first successful kidney transplant using a deceased donor (Peter Bent Brigham Hospital, Boston, Massachusetts)
1963 liver transplantation is tried
1963 lung transplantation is attempted
1966 first successful pancreas transplant (University of Minnesota, Minneapolis, Minnesota)
1967 first successful liver transplant (University of Colorado, Denver, Colorado)
1967 first successful heart transplant (Groote Schuur Hospital, Cape Town, South Africa)
1978 cyclosporine introduced in England as a new immunosuppressant (anti-rejection drug) for patients
1981 first successful heart-lung transplant (Stanford Medical Center, Stanford, California)
1983 lung transplant (Toronto, Ontario), which was the first successful lung transplant in the world
1985 first patient to survive an artificial heart implant as a "bridge" to transplant (University of Arizona, Tucson, Arizona)
1985 the international Council of the Transplantation Society issues guidelines prohibiting the buying or selling of organs and tissues
1986 double lung transplant (Toronto, Ontario), the world's first successful double lung transplant
1988 liver-bowel transplant (London, Ontario), which was the first successful liver-bowel transplant worldwide
1988 two patients are transplanted when a donated liver is cut in half (Paul Brousse Hospital, Villejuif, France)
1989 a child receives a portion of the parent's liver for the first living liver donation (Sao Paulo, Brazil)
1989 the First International Congress on Ethics, Justice, and Commerce in Transplantation is held in Ottawa, Canada, with consensus on a number of resolutions
1990 a new anti-rejection drug, FK506, becomes available
1990 girl, 12, receives part of her mother's lung for the first living-donor lung transplant. (Stanford Medical Center, Stanford, California)
1993 a heart transplant patient died suddenly, and this heart was then transplanted into another patient (one heart has supported three lives) (University Hospital, Zurich, Switzerland)
1995 a patient with Gardner's syndrome has all his abdominal organs removed in order to receive a new kidney, pancreas, stomach,liver, large and small bowel, and one iliac artery (University of Miami, Miami, Florida)
1997 the Multi-Organ Transplant Program at London Health Sciences Centre transplants the liver, bowel, stomach, and pancreas into a 5-month-old infant, the world's youngest recipient of a multi-organ transplant (London, Canada)
1999 a double transplant is performed when a son gives part of his liver and one of his kidneys to his father (Sao Paulo, Brazil)
2000 the islet transplantation team at University of Alberta Hospital makes international news with the release of the "Edmonton Protocol," for treatment of type I diabetes (Edmonton, Alberta)
2003 doctors at the Charité Hospital simultaneously transplant 8 organs (liver, pancreas, stomach, duodenum, small intestine, partial large intestine, kidney and adrenal gland) to treat Crohn's disease in a 36-year-old woman (Berlin, Germany)
2005 a 38-year-old woman receives a partial face transplant, including nose, lips and chin (Amiens, France)
2006 for the first time, a five-way kidney swap among ten individuals is coordinated. The marathon, 10-hour surgeries occupied six operating rooms staffed by 12 surgeons, 11 anesthesiologists and 18 nurses (Johns Hopkins Hospital, Baltimore, USA)
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