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Disclaimer to the On-line Edition
This Manual has been designed for use in the NICU at London Health Sciences Centre (LHSC), London, Ontario, Canada, and represents clinical practice at this institution. The information contained within the Manual may not be applicable to other centres. If users of this Manual are not familiar with a drug, it is recommended that the official monograph be consulted before it is prescribed and administered. Any user of this information is advised that the contributors, Editor and LHSC are not responsible for any errors or omissions, and / or any consequences arising from the use of the information in this Manual.

SULFACETAMIDE SODIUM
(Sodium Sulamyd(R))

Indication

  • use in the treatment of conjunctivitis and superficial ocular infections caused by susceptible organisms

Pharmacology

  • acts through inhibition of bacterial folic and synthesis

Side Effects

  • local irritation, stinging, burning
  • hypersensitivity reaction

Miscellaneous

  • do NOT use solutions if colored
  • overgrowth of non-susceptible organisms may occur

Dose

  • 10% ophthalmic solution - 1 to 2 drops into affected eye(s) (lower conjunctival sac) up to every 2 to 3h
  • 10% ophthalmic ointment - small amount into affected eye(s) (lower conjunctival sac) 2 to 4 times daily

Supplied

  • 10% ophthalmic ointment
  • 10% or 30% ophthalmic solution (Note: 30% ophthalmic solution may be very irritating - 10% is usual strength for neonates. All orders for ophthalmic solution MUST specify strength.)

References

  1. Krogh CME et al (ed): Compendium of Pharmaceuticals and Specialties, Canadian Pharmaceutical Association, 1992.
  2. Bhatt DR, Furman GI, Reber DJ et al: Neonatal Drug Formulary, 1990-1991, 2nd Edition, Fontana, California 92334.
  3. Taketomo CK, Hodding JH and Kraus DM: Pediatric Dosage Handbook, Lexi-Comp Inc., Cleveland, 1992.



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