Studies and Clinical Trials

Your Neurologist is familiar with the current research available and who is eligible to participate.  You may be approached to consider enrolling.  You will always be given information regarding the study.   Your participation is voluntary.  You may withdraw from the study at any time, but we ask that you please inform us as to the reason.

During any study you are followed very closely by the Neurologist, Nurse and Research Coordinator.  We adhere to global, national, provincial and hospital guidelines and ethics.

With your consent, we also maintain a Motor Neuron Disease Clinical and Research Database.   Your information regarding health history and care is secured indefinitely  for future research projects.

 

  • Phase 3 Clinical Trial assessing ceftriaxone as a treatment for ALS

A NIH (National Institute of Health)-sponsored U.S. and Canada clinical trial assessing the efficacy and safety of administering ceftriaxone intravenously twice a day to treat ALS (Amyotrophic Lateral Sclerosis).  Ceftriaxone is a well known antibiotic which is hypothesized to reduce excitotoxicity of motor neurons.

  • Natural History study of patients with PLS (Primary Lateral Sclerosis)

This study evaluates how PLS patients change over time.  The study includes annual visits, a single skin biopsy, blood work, urine studies and multiple questionnaires about environmental exposures.

  • Phase 3 international clinical trial of dexpramipexole for ALS

This study is evaluating dexpramipexole, which is hoped to be neuroprotective, to treat ALS.   Dexpramipexole is a pill which is only available through this clinical trial at this time.

LHSCPatients, Families & Visitors

Last Updated May 25, 2012 | © 2007, LHSC, London Ontario Canada