Esophageal Cancer Treatment Study

Title: A Prospective Randomized Phase III Trial Comparing Preoperative Chemoradiation Therapy (Cisplatin, 5-FU and Radiotherapy followed by Surgery) to Surgery followed by Postoperative Chemoradiation (Cisplatin, Epirubicin, 5-FU, Radiotherapy) for Esophageal Cancer (The QUINTETT Study)

The purpose of this study is to compare the results of preoperative chemotherapy and radiation followed by surgery to surgery followed by postoperative chemotherapy and radiation based on surgical pathological staging (tumor testing done by a pathologist to determine how advanced the cancer is) in order to treat your esophageal cancer and to see which is better. There have been some early studies that have indicated that surgical resection (surgery to remove the cancer) followed by chemotherapy and radiation is superior and may help to prevent the cancer returning. This study is being done because we do not know which of these two treatments is better.

Have Any Questions?   Please contact:

Deb Lewis
Clinical Research Coordinator
LHSC Victoria Hospital
E2-003
(519) 685-8500 ext 75685
deb.lewis@lhsc.on.ca