Title: A Phase III Randomized Trial of Lobectomy versus Sublobar Resection for

Small (less than or equal to 2 cm) Peripheral Non-Small Cell Lung Cancer

The purpose of this study is to try to find a different way of doing surgery for lung cancer in patients who have small tumors with no evidence of spread. Recent studies have questioned whether removing a larger portion of the lung containing the tumor offers much better control of the cancer than removing a smaller section of the lung. The purpose of this clinical trial is to look at whether removal of a small section of lung (called a sub-lobar resection) is equal to a lobectomy (larger resection). This clinical trial will be studying the overall effects (good and/or bad) of a sublobar resection (smaller segment of your lung) compared to a lobectomy (entire lobe of your lung).

Sublobar or Wedge Resection

Lobectomy