Trace Elements Laboratory
A Joint Venture of London Health Sciences Centre and St. Joseph's Health Care London
Bismuth (Bi)
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Atomic Number:

83

Atomic Symbol:

Bi

Atomic Weight: 208.9804
Electron Configuration: [Xe]6s24f145d106p3

Bismuth has been known since Claude Geoffroy distinguished it from lead in 1753. Bismuth is a heavy metal, that is not an essential element.  It is mainly used in the production of alloys especially of those with low melting points. Toxicity in industry has not been reported. All lethal intoxication's are attributed to the therapeutic uses of Bismuth compounds.

Medical uses of bismuth compounds are largely responsible for excessive exposure to bismuth. These compounds include formulations which are used as antiseptics, astringents, and antacids, and preparations for the treatment of duodenal ulcers and peptic diseases (Helicobacter pylori infections). Some compounds include bismuth subsalicylate (Pepto-Bismol) to control GI upset, diarrhea, and irritable bowel syndrome, and bismuth subgallate (Colo-fresh) to control fecal odours associated with colostomies, ileostomies and fecal incontinence. Toxicity results in renal damage, encephalopathy and peripheral neuropathy. As bismuth is also used in paint pigments, exposure of occupational workers in this industry can occur. Levels in plasma, urine and hair have been used to monitor excessive exposure.

Sample Requirements (click on cell)
 

Reference range
 

Analyte Bismuth
Random Urine
Random Urine
24 hr Urine
Hair
0.00 - 0.34 nmol/L
0.0 - 44.1 nmol/mol creat
0.00 - 0.48 nmol/d
 0 - 0.45 nmol/g

Method of Analysis:  High Resolution ICP/MS

Test available:  Monday - Friday 0800 - 1600 h
Turnaround Time:  Average 5-10 days
Maximum 10 days


 
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January 31, 2012