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Section Head -
Dr. C. Howlett MD
The division of Molecular
Pathology, the newest in the Department, provides a growing
and important bridge between diagnostic histopathology and
genetic pathology. The applications for this technology
and its impact on patient care continue to see a great deal
of growth.
LIST OF TESTS
The following tests
are currently being offered in the Molecular Pathology Lab
LHSC. Please contact Molecular Pathology Laboratory for
specific information (x36305)
- Lymphoma: Immunoglobulin
heavy chain gene rearrangement a
- Lymphoma: T
cell receptor gama gene rearrangement a
- Lymphoma: BCL-2-mbr
gene rearrangement a
- Lymphoma: BCl-1
gene rearrangement a
- ApoE genotyping
Alzheimer (by PCR and RFLP) a
- Hemochromatosis-C282Y
mutation a
- Hemochromatosis-H63D
mutation a
- Hemochromatosis-S65C
mutation a
- Hemochromatosis-TFR2
mutation a
- Hfe (HLA-H)
genotyping by sequencing PCR product a
- Yersinia pseudo
tuberculosis detection a
- Yersinia enterocolitica
detection a
- Tyrosinase
mRNA (melanoma) - RT-PCR b
- Muc 18 mRNA
(melanoma) - RT-PCR b
- Tyrosine hydroxylase
mRNA (neuroblastoma) - RT-PCR b
- Telomerase
mRNA (malignant tumours) - RT-PCR b
- H-TERT mRNA
(malignant tumours) - RT-PCR b
- Gelactin -3
mRNA (thyroid tumours) - RT-PCR b
- Ret/PTC 1,
2, 3 mRNA (thyroid tumours) - RT-PCR b
- PSA mRNA by
RT-PCR (prostate cinoma) b
- LOH (anaplastic
gliomas) PCR b
Specimen Requirement
a = fresh/frozen/formalin fixed paraffin embedded tissue
or blood
b = fresh/frozen/or cytolyte TM fixed
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