Mitochondria are essential organelles. Diseases of the mitochondria affect many organs and organ systems in the body. Click on a part of the body to see the common symptoms of mitochondrial disease associated with that organ.
Mitochondrial diseases are extremely rare conditions with prevalence being approximately 12 in 100 000 people. Mitochondria are organelles found in nearly all body cells. Therefore disorders of mitochondria are typically multisystemic, meaning they affect many organs and areas of the body.
Mitochondria are of course the energy powerhouses of the cell. A disease of these organelles disrupts their ability to make energy for the cell. This lack of energy to areas that demand it makes cells and eventually organs dysfunctional. This energy deficit can be considered the root cause of the symptoms observed in mitochondrial disease.
Sensorineural hearing loss
Retinitis Pigmentosa – a group of diseases of the eye characterized by
A group of disorders of the digestive tract caused by improper functioning of muscles that help move food down the tract
This causes various symptoms of the digestive system, often caused by bacterial infections
Various forms of liver disease including jaundice, which causes a yellowish discolouration of the skin as a result of an excess chemical called bilirubin
Exercise intolerance and fatigue