- treatment of hyperkalemia
- removes potassium from the body by exchanging sodium ions for potassium, particularly in the large intestine; potassium-containing resin is then excreted; small amounts of other cations such as calcium and magnesium may be lost during treatment: sodium retention may occur
- 1 g of resin binds approximately 1 mmol (1 mEq) of K+
- reduction of serum potassium level occurs within 2 to 24 hours
- hypokalemia, hypocalcemia, hypomagnesemia, sodium retention, vomiting, constipation
- may cause fecal impaction
- monitor serum potassium, sodium, calcium, and magnesium
- observe for hypokalemia - irritability, muscle pain and weakness, dampened T-wave on ECG
- watch bowel function, check daily
- calculated on exchange rate of 1 mmol of potassium per gram of resin: usual dose is 1 g/kg per rectum q2-6h
- rectal: mix powders with 5-10 mL of sterile water and give as an enema using a 10 mL syringe and 5 Fr. feeding tube; deliver at a rate of 1 mL/kg/min
- pinch buttocks while withdrawing tubing and for 3 to 5 minutes after
- 1 g powders stocked in the unit
- other weights of powders prepared by Pharmacy as needed
- Gomella TL (Ed): Neonatology - Management, Procedures, On-Call Problems, Diseases, Drugs, 1992, Appleton and Lange, Norwalk, Connecticut.
- Bhatt DR, Furman GI, Reber DJ et al: Neonatal Drug Formulary, 1990-1991, 2nd Edition, Fontana, California 92334.
- Taketomo CK, Hodding JH and Kraus DM: Pediatric Dosage Handbook, Lexi-Comp Inc., Cleveland, 1992.
- Taeusch WH Ballard RA and Avery ME (ed): Schaffer and Avery's Diseases of the Newborn, WB Saunders Co, Toronto, Ontario; 6th Edition, 1991.