SWORBHP is currently involved in the following research studies that are in the development phase, data collection phase, data analysis phase or being prepared for dissemination. Listed are the Principal Investigators along with any Co-investigators that are affiliated with SWORBHP.
A Pragmatic Strategy Empowering Paramedics to Assess Low-Risk Trauma Patients with the Canadian C-Spine Rule (CCR) and Selectively Transport them Without Immobilization - (C. Vaillancourt, M. Davis, P. Bradford)
The investigators will evaluate the possibility and benefits of allowing paramedics to use the CCR in the field in 12 communities from across Ontario. The investigators will also measure the impact on the ED, and how much money could be saved if more paramedics were allowed to use the CCR. The investigators will also assess if sex, age, language barriers, or living far from the hospital (long transport time) will affect the outcomes of the study- dissemination preparation
Double Sequential External Defibrillation for Refractory VF - DOSE VF - (S. Cheskes, M. Davis)
Multi-centre randomized control trial examining if double sequential defibrillation or vector change defibrillation results in a significant improvement in neurologically intact survival in patients with refractory VF - data collection phase
CanROC Epinephrine Dose: Optimal versus Standard Evaluation Trial - EpiDOSE - (S. Lin, M. Davis, P. Bradford)
A prospective, multi-centre, single-blinded, randomized controlled trial to determine if treatment with a low cumulative dose of epinephrine compared to treatment with a standard cumulative dose of epinephrine during resuscitation in adult out-of-hospital cardiac arrest patients with ventricular fibrillation or pulseless ventricular tachycardia improve survival to hospital discharge - development phase
Canadian EMS Syncope Risk Score Validation - (I. Drennan, M. Davis)
The purposeof this study is to evaluate the performance of the Canadian EMS Syncope Risk Score (CESRS) for use by paramedics in the prehospital setting to accurately predict the risk of significant adverse event occurring within 30 days for patients with syncope - development phase
Pediatric Out-of-Hospital Cardiac Arrest Resuscitation: Evaluation of IM Epinephrine - The PRIME Trial - (J. Tijssen, M. Davis)
The PRIME Trial is a pragmatic, two-arm, open-label, prospective stepped-wedge cluster randomized control trial (SW-CRCT). The purpose of this trial is to determine if IM epinephrine, added to standard of care, will improve time to ROSC (primary outcome) compared to standard of care alone - development phase
Hyperkalemia Medical Directive QA Project - (R. Labelle, M. Davis, D. Eby)
This study aims to assess how the provincial medical directive for hyperkalemia is being adhered to, when is the protocol being implemented, and how does it vary within the region - data analysis phase
Paramedics’ ability to determine diagnosis and most appropriate destination in patients who activate 9-1-1 - (M. Lewell, J. Loosely, M. Davis)
This study analyses the accuracy of diagnoses made by paramedics and their ability to independently identify appropriate destinations for their patients - dissemination phase
Canadian Resuscitation Outcomes Consortium - CanROC/OPALS -(C. Vaillancourt, M. Davis, P. Bradford)
The Ontario Prehospital Advanced Life Support Study (OPALS) is a long-standing collaboration among several Ontario communities. Since 1994 this research collaboration, lead out of the Ottawa Hospital Research Institute has been collecting key information on out-of-hospital cardiac arrest and traumatic injury - data collection, analysis, dissemination phases
Canadian Sudden Cardiac Arrest Network - C-SCAN OPALS - (C. Vaillancourt, M. Davis, P. Bradford)
The overall objective of the project is to develop an accurate, comprehensive, population based database of sudden cardiac arrest patients to measure the true burden of SCA within the Ottawa-OPALS Network of seven Ontario Communities (Ottawa, London, Windsor, Niagara, Thunder Bay and Kingston) - data collection, analysis, dissemination phases
