Fertility drugs enhance the chances of conceiving by stimulating the ovaries to produce more eggs. However, more than one egg can be fertilized increasing the probability of multiple pregnancies.
Twin pregnancies occur in approximately 8% of patients using clomiphene citrate while the risk of triplet pregnancy is less than 1%. The risk of twin pregnancies with injectable gonadotropins is approximately 20% while the risk of triplets can be between 1% and 3%.
In IVF the risk of multiple pregnancies depends on the number of embryos transferred back to the uterus. Patient and doctor can discuss the risk of multiples and decide on the number of embryos that is appropriate considering both patient’s choice and medical indications.
Multiple pregnancies are associated with significant risks, including pregnancy diabetes, maternal bleeding, premature labor, premature delivery, Caesarean delivery (C-section) and pregnancy-induced high blood pressure.