||vasodilator - antihypertensive agent
- reduces systemic vascular resistance by direct relaxation of vascular smooth muscle
- reduces pulmonary vascular resistance
- dilates renal arterioles
- Afterload reduction:
- 5 mg-25 mg/hr (titrated to effect)
- Intermittent doses
- IV Direct:
- maximum rate of injection 5 mg/min
- IV Infusion:
- hypovolemia should be corrected concurrently with therapy
- should be weaned off
- increased myocardial oxygen consumption
- peripheral neuritis as evidenced by numbness, tremor, agitation, anxiety
- rheumatoid syndrome---systemic lupus erythematosus like syndrome
- risk of hemorrhage in patients with cerebral or abdominal aneurysms due to speed of blood flow
- may worsen a pulmonary shunt
- HR, ECG
- CVP, PCWP
- cardiac index
- PVRI, SVRI
- blood gases, Sp02
- joint appearance and mobility
- May be administered by IV infusion by any RN.
- May be administered IV direct by an approved nurse in the CCTC at a rate < 5mg/min.
- May be titrated by an approved nurse in the CCTC.
- Central line is preferred.
- Continuous infusion must be administered via an infusion pump.
- Should not be infused via the proximal injectate port (blue) of the Swan Ganz catheter.
- Patient requires placement of an arterial line to monitor BP if administered as a continuous infusion.