stimulates beta adrenergic receptors

• positive inotrope
• positive chronotrope
• positive dromotrope
• bronchodilator
• causes vasodilation resulting in reduced peripheral vascular resistance (unlike epinephrine, has no alpha properties)

• Bolus dose:
• 0.05 - 0.2 mg IV direct
• Infusion:
• 0.05 - 0.2 ug/kg/min (approx. 1 - 4 ug/min)

• IV Direct:
• dilute 1 mL of 1:5000 (0.2 mg/mL) to a volume of 10 mL with NS/D5W (final concentration of 20 ug/mL)
• IV Infusion:
• 1mg/500 mL NS, D5W, RL
• hypovolemia, acidemia, and hypoxemia should be corrected concurrently with initiation of therapy
• should be weaned off

• tachycardia
• arrhythmias
• hypotension or hypertension
• increased myocardial oxygen consumption
• increased blood glucose

• isoproterenol + theophylline = decreased serum theophylline levels

• HR, ECG rhythm
• BP
• urine output
• cardiac index
• blood gases
• PWP
• arterial lactate
• blood glucose
• electrolytes

• May be administered by IV infusion by an approved nurse in CCTC.
• May be titrated by an approved nurse in the CCTC.
• Must be administered via a central line.
• Continuous infusion must be administered via an infusion pump.
• Should not be infused through the proximal injectate port (blue) of the Swan Ganz catheter.
• Patient requires placement of an arterial line to monitor BP.