stimulates beta adrenergic receptors
- positive inotrope
- positive chronotrope
- positive dromotrope
- causes vasodilation resulting in reduced peripheral vascular resistance (unlike epinephrine, has no alpha properties)
- Bolus dose:
- 0.05 - 0.2 mcg/kg/min (approx. 1 - 4 mcg/min), titrate to effect
- IV Direct:
- dilute 1 mL of 1:5000 (0.2 mg/mL) to a volume of 10 mL with NS/D5W (final concentration of 20 mcg/mL)
- IV Infusion:
- 5mg/250 mL NS, D5W, RL (20 mcg/ml)
- hypovolemia, acidemia, and hypoxemia should be corrected concurrently with initiation of therapy
- should be weaned off
when using to correct bradyarrhythmias or as an inotrope, monitor carefully for hypotension
- hypotension or hypertension
- increased myocardial oxygen consumption
- increased blood glucose
- isoproterenol + theophylline = decreased serum theophylline levels
- HR, ECG rhythm
- urine output
- cardiac index
- blood gases
- arterial lactate
- blood glucose
- May be administered by IV infusion by an approved nurse in CCTC.
- May be titrated by an approved nurse in the CCTC.
- Must be administered via a central line.
- Continuous infusion must be administered via an infusion pump.
- Should not be infused through the proximal injectate port (blue) of the Swan Ganz catheter.
- Patient requires placement of an arterial line to monitor BP.