phenylephrine + alpha blocking agents = blockade of vasopressor effect
phenylphrine + other sympathomimetics = increased risk of toxicity
heart rate and ECG rhythm
central or mixed venous oxygen saturation
cardiac index if monitored
SVRI if monitored
changes in skin colour or tempurature
Adult Critical Care Protocol:
May be administered IV direct or by IV infusion by a nurse in Adult Critical Care.
May be titrated by a nurse in Adult Critical Care.
Must be administered via central venous access device; in emergency situations may be temporarily infused through a peripheral vasuclar access device until a central venous line can be established.
Patient requires placement of an arterial line to monitor BP.
Continuous infusions must be administered by infusion device and the pump library must be enabled.
Should not be infused via the proximal injectate port (blue) of a pulmonary artery catheter. If this is the only available central venous line, it may be administered through the proximal injectate port but thermodilution cardiac output measurements must not be measured during infusion).
Lynne Kelly, Pharmacist, CCTC
Brenda Morgan, Clinical Nurse Specialist, CCTC Last Update:
September 20, 2018
Reviewed: January 12, 2017
Revised: March 3, 2017, updated September 17, 2018