Clinical Trials

 

Current clinical trials by disease site

Who we are

The services we offer...

Some of our achievements...

The CRU Team...

We are partners and collaborators with...

Who we are

The Clinical Research Unit (CRU) coordinates and supports protocol management and clinical/translational research projects undertaken by the academic/clinical staff of LRCP. Clinical research plays a vital role in lessening the growing burden of cancer in Ontario, the overall mission of Cancer Care Ontario.

Clinical Research at the LRCP is carried out through ten disease-specific multidisciplinary teams: breast, gastrointestinal, genitourinary, gynecological, head and neck, central nervous system, skin, thoracic, sarcoma, hematological, and through the supportive care program.

The services we offer

The CRU has extensive experience across a spectrum of clinical trials activities, and offers the following services:

  • access to a large patient population across multiple disease sites
  • study design, protocol development and methodological advice
  • data base development and support and form design
  • statistical support including sample size, analysis, and interpretation of results
  • management of ethics documentation, including initial submissions, amendments and safety reports
  • completion of regulatory documentation
  • patient recruitment
  • case report form completion
  • long term follow-up for adjuvant trials
  • design and maintenance of tumour bank and data base projects
  • sample collection for pharmacokinetic studies
  • quality assurance
  • liaison with granting agencies, the pharmaceutical industry, and governments
  • National and International Central Databases

Some of our achievements

  • Operational since 1982 as part of a University-based comprehensive cancer centre
  • Regularly recruit 250-400 patients each year to 50 to 70 active trials
  • Unit has developed close collaborations with Cooperative Groups and Pharmaceutical Industry
  • Implemented quality control procedures which have been validated by multiple external audits (Cooperative Group, Industry, FDA)
  • Staff have developed and published an innovative patient assessment record (PAR) of treatment toxicities, widely adopted by other clinical research programs
  • Major participation in studies which resulted in changes in standards of care

Skilled and dedicated people make up the CRU team:Bobbi

Supervisor,

Bobbi Smuck, CCRP

Bobbi has 20 years experience within the unit. She is responsible for daily operations, ensuring initial and continued regulatory approval of all protocols, and adherence to good clinical practice within LRCP administration and clinics.

The CRU Team

  • Clinical Research Associates are responsible for the organization, implementation, coordination and documentation of clinical research projects.
  • Clinical Trials Assistants coordinate the follow-up phase for clinical trials subjects, complete case documentation and assist Clinical Research Associates with the coordination of active research projects.
  • Data Management Coordinators maintain central databases for provincial, national and international multi-centre studies.
  • A Biostatistician works with the LRCC professional/academic staff on the methodological and statistical aspects of their research.
  • A Statistical Database Coordinator creates data management systems to facilitate data collection and analyses of retrospective and prospective LRCC-based research projects.
  • An Ethics Regulatory Coordinator is responsible for initial and ongoing ethics approval submissions.
  • An Administrative Assistant is responsible for initial and ongoing ethics approval submissions, collection of workload stats, and administrative/secretarial support for all CRU activities.

We are partners and collaborators with

Helpful Links:

Canadian Cancer Society – Clinical Trials

ClinicalTrials.gov (U.S.A.)

Ontario Cancer Trials

The Division of Urologic Surgery, Western University

 

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Last Updated May 22, 2012 | © 2007, LHSC, London Ontario Canada