Clinical Trials

Trial Name Description
Checkmate-227 Dr. Mark Vincent
An Open-Label, Randomized, Phase 3 Trial of Nivolumab, or Nivolumab plus Ipilimumab, or Nivolumab plus Platinum Doublet Chemotherapy versus Platinum Doublet Chemotherapy in Subjects with Chemotherapy-Naive Stage IV or Recurrent Non-Small Cell Lung Cancer
PET-BOOST Dr. David Palma
A Randomized Phase II Trial to Assess the Efficacy and Safety of Selective Metabolically Adaptive Radiation Dose Escalation in Locally Advanced Non-Small Cell Lung Cancer Receiving Definitive Chemoradiotherapy.
NRG CC003 Dr. Alex Louie
Randomized Phase II/III Trial of Prophylactic Cranial Irradiation with or without Hippocampal Avoidance for Small Cell Lung Cancer.
A Randomized Phase III Trial of Palliative Radiation of Advanced Central Lung Tumors with Intentional Avoidance of the Esophagus
Checkmate 577 Dr. Mark Vincent
A Randomized, Multicenter, Double Blind, Phase III Study of Nivolumab or Placebo in Subjects with Resected Lower Esophageal, or Gastroesophageal Junction Cancer.
BR.31 Lung Dr. Sara Kuruvilla
A Phase III Retrospective, Double-Blind, Placebo-Controlled, Randomized Study of Adjuvant MEDI4736 in Completely Resected Non-Small Cell Lung Cancer
RELAY - JVCY Lung Dr. M. Vincent
A Multicentre, Randomized, Double-Blind Study of Erlotinib in Combination with Ramucirumab in Previously Untreated Patients with EGFR Mutation-Positive Metastatic Non-Small Cell Lung Cancer
LUSTRE Lung Dr. Alex Louie
A Randomized Trial of Medically-Inoperable Stage I Non-Small Cell Lung Cancer Patients Comparing Stereotactic Body Radiotherapy Versus Conventional Radiotherapy
IND.227 Dr. Mark Vincent
A Phase II Randomized Study of Pembrolizumab in Patients with Advanced Malignant Pleural Mesothelioma.
A Phase II Trial Measuring the Integration of Stereotactic Radiotherapy plus Surgery in Early Non-Small Cell Lung Cancer
STOP-NSCLC Dr. David Palma
Sterotactic Radiotherapy for Oligo-Progressive Non-Small Cell Lung Cancer
NRG-LU002 Dr. Alex Louie
"not yet open" Maintenance Systemic Therapy Versus Consolidative Stereotactic Body Radiation Therapy (SBRT) Plus Maintenance Systemic Therapy for Limited Metastatic Non-Small Cell Lung Cancer (NSCLC): A Randomized Phase II/III Trial.
SUNSET Dr. David Palma
"not open yet" SUNSET: SBRT for Ultra-central NSCLC- a Safety and Efficacy Trial.

This information is updated by the Clinical Research Unit

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Last Updated August 3, 2007 | © 2007, LHSC, London Ontario Canada