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MD University of Calgary
Room A4-140, Victoria Research Laboratory
London Regional Cancer Program
790 Commissioners Road East
London, ON N6A 4L6
Phone: (519) 685-8500 Ext. 53293
Fax: (519) 685-8616
Division of Gastroenterology
Key Words: general gastroenterology, inflammatory bowel diseases, colorectal cancer
Descriptions of Clinical Activities: I am a clinician scientist who practices general gastroenterology and have a special interest in chronic inflammatory bowel diseases and colorectal malignancy.
Key Words: stem cells, inflammation, colorectal cancer, inflammatory bowel diseases
Description of Research Activities: Our research focuses on identifying the cellular origin of colorectal cancer by characterizing the intestinal and colonic stems cells of the gut. We are focused on understanding the fundamental processes regulating normal and mutated intestinal/colonic stem cells and aim to define the role of these stem cells in tissue regeneration and carcinogenesis. We utilize a range of approaches from transgenic mouse models to in vitro "mini-guts" to elucidate the key pathways important in cancer and tissue repair.