Specimen and Shipping Instructions

For sample collection please visit local blood draw centre.

Specimen and Shipping Instructions

Ordering

Please carefully read the recommended specimen and shipping instructions before ordering a test. Incomplete and/or illegible requisitions and/or specimen labeling will result in testing being suspended until the complete information can be obtained. Requisitions must be signed by the referring physician.

Prenatal Testing Guide

Specimen Requirements

Preferred Specimen by Test

Test

Preferred Specimen

Collection tube

Cytogenetics – karyotyping (constitutional and oncology) and FISH testing

Blood or bone marrow

NaHep (green top)

Cytogenetics - microarray

Blood, DNA

EDTA (lavender top)

Cytogenetics – microarray family follow up studies*

Blood

NaHep (green top)

Cytogenetics - QFPCR

Blood, DNA

EDTA (lavender top)

Cytogenetics – BMT Chimerism

Blood, DNA

EDTA (lavender top)

Molecular – germline (HCP, FH, Epilepsy, etc)

Blood, DNA

EDTA (lavender top)

Molecular - mitochondrial

Blood

Blood: EDTA (lavender top)

Molecular – mitochondrial follow up

Urine, Muscle tissue

Urine/Muscle: Sterile container

Molecular – known variant testing

Blood, other tissues

Blood: EDTA (lavender top)

Other tissue: Sterile container/ Chang’s media, please contact the lab

Molecular – hematological oncology

Bone marrow, blood

EDTA (lavender top)

Molecular – ctTNA for NSCLC

Blood

Streck (see info sheet)

*Please note, follow up microarray studies require parental sample(s). Sending just the proband sample is not useful.

Additional Specimen Information by Type

Type

Notes

Shipping Information

Blood in NaHep or EDTA

2-4 ml for adults, 0.5ml if necessary (newborns)

Room Temperature, must arrive within 5 days

Cord Blood in EDTA

Maternal Cell Contamination Studies are recommended. Please send 2mL maternal peripheral blood sample in EDTA (lavender top).

Room Temperature, must arrive within 5 days

DNA

Please specify concentration and method of extraction.

Room Temperature, must arrive within 5 days

RNA/DNA (Total Nucleic Acid)

Please specify concentration and method of extraction.

Ship frozen on dry ice, must arrive within 48 hours

Urine

For mitochondrial follow up testing only. Please provide 30mL of urine in a sterile container.

Urine samples should be refrigerated; samples should be frozen if receipt will occur > 2 days post collection.

Muscle tissue

For mitochondrial follow up testing only.

Must be shipped frozen on dry ice. Do not ship on Fridays. If arriving in lab same day, send on ice.

Prenatal specimens

Please see our Prenatal Testing Guide, above

Other tissues

Please contact the lab to inquire about additional sample types

Shipping Instructions

Lab Hours: 0700 to 1700 Monday to Friday.

Sample Handling: samples should be shipped at room temperature overnight by courier and according to current standards for Transportation of Dangerous Goods, and in IATA Packing instruction 650 summarized as:

  • a watertight primary receptacle
  • a watertight secondary receptacle with sufficient absorbent material to absorb the fluid in the primary receptacle.
  • an outer package of adequate strength for its intended use.

Samples requiring RNA extraction must be less than 48 hours old on arrival in the lab or they will be deemed inadequate.

Samples requiring DNA extraction only must be less than 5 days old on arrival in the lab or they will be deemed inadequate.

Mailing Address: (also printed on requisition)

Molecular Genetics Laboratory
Victoria Hospital, Room B10-123
London Health Sciences Centre
800 Commissioners Rd E.
London, Ontario, Canada
N6A 5W9

Cytogenetics Laboratory
Victoria Hospital, Room B10-114 
London Health Sciences Centre
800 Commissioners Rd. E. 
London, Ontario, Canada 
N6A 5W9