The first step in treatment is to determine the possible cause(s) and treat as required. Medications may be used after considering the cause(s) and clinical presentation.
At the present time , we do not know whether treating delirium with antipsychotic medications will result in better patient outcomes.
While the patient's behaviour may improve, causing the ICDSC score to fall during the treatment of delirium, we do not know if there is a correlation between the ICDSC score and the degree of delirium. More research is needed to answer this question.
We do know the correct interpretation of these changes. The patient may still be experiencing delirium that is being masked by medication or the patient may have subsyndromal delirium. More research is needed to correlate changes in the clinical scores to the delirium trajectory.