| Name: |
ADENOSINE (AdenocardR) |
| Classification: |
Antiarrhythmic:
- produces short acting AV block to aid in the diagnosis of supraventricular tachycardias
- may convert PSVT to sinus rhythm when verapamil is not effective or is contraindicated
|
| Dose: |
Bolus Dose:
- Administer each dose into a port as close to the patient as possible.
Administer each dose undiluted by IV direct. Administer within 1-2 seconds.
- After each IV direct dose, administer a 20 mL sodium chloride 0.9% flush. Administer the flush as quickly as possible.
First dose:
6 mg IV direct by rapid bolus
Second dose if no response within 1-2 minutes:
12 mg IV direct by rapid bolus
Third dose if no response within 1-2 minutes:
12 mg IV direct by rapid bolus
Maximum total dose of 30 mg.
|
| Administration: |
IV Infusion:
|
| Adverse Effects: |
- cardiovascular
- sinus bradycardia, sinus arrest, atrial fibrillation, AV block (usually < 1 minute)
- hypotension
- non-cardiovascular
- flushing and dyspnea
- headache, cough, malaise, or nausea usually lasting <1 minute due to very short half life
|
| Drug Interactions: |
- adenosine + aminophylline/theophylline = decreased adenosine effect
- adenosine + digoxin = bradycardias and increased AV blocks
- adenosine + verapamil = bradycardias and increased AV blocks
- adenosine + beta blockers = bradycardias and increased AV blocks
|
| Monitoring Therapy: |
- continuous heart rate and cardiac rhythm
- blood pressure
|
| Adult Critical Care Protocol: |
- May be administered IV direct by an Adult Critical Care Nurse.
- A physician must be present during administration.
- This drug must be given by rapid BDC bolus.
- Resuscitation equipment should be on hand.
|
